EC Number | Application | Comment | Organism |
---|---|---|---|
4.6.1.13 | molecular biology | enzyme is used as a tool in the studies of GPI-anchored proteins | Staphylococcus aureus |
4.6.1.13 | molecular biology | enzyme is used as a tool in the studies of GPI-anchored proteins | Bacillus cereus |
4.6.1.13 | molecular biology | enzyme is used as a tool in the studies of GPI-anchored proteins | Bacillus thuringiensis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.6.1.13 | extracellular | - |
Bacillus cereus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.13 | additional information | Listeria monocytogenes | the enzyme contributes to listerial infection of epithelial cells and macrophages as a virulence factor cooperating with other factors such as listeriolysin O and phosphatidylcholine-preferring phospholipase C | ? | - |
? | |
4.6.1.13 | additional information | Bacillus thuringiensis | the enzyme exhibits cytotoxicity against some cultivated cells | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.13 | Bacillus cereus | - |
- |
- |
4.6.1.13 | Bacillus thuringiensis | - |
- |
- |
4.6.1.13 | Listeria monocytogenes | - |
- |
- |
4.6.1.13 | Staphylococcus aureus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.6.1.13 | culture medium | - |
Bacillus cereus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.13 | additional information | the enzyme contributes to listerial infection of epithelial cells and macrophages as a virulence factor cooperating with other factors such as listeriolysin O and phosphatidylcholine-preferring phospholipase C | Listeria monocytogenes | ? | - |
? | |
4.6.1.13 | additional information | the enzyme exhibits cytotoxicity against some cultivated cells | Bacillus thuringiensis | ? | - |
? | |
4.6.1.13 | phosphatidylinositol + H2O | at first the enzyme catalyzes phosphate transfer within the molecule of phosphatidylinositol from glycerol OH to 2-OH of myo-inositol, resulting in diacylglycerol and myo-inositol 1,2-cyclic phosphate. Next myo-inositol 1,2-cyclic phosphate is hydrolyzed by the enzyme to inositol 1-phosphate. Since the reaction rate of the first step (phosphotransferase) is 1000 times as much as that of the second step (cyclic phosphodiesterase) myo-inositol 1,2-cyclic phosphate accumulates as one of the major products during enzyme action | Staphylococcus aureus | diacylglycerol + myo-inositol 1,2-cyclic phosphate | - |
? | |
4.6.1.13 | phosphatidylinositol + H2O | at first the enzyme catalyzes phosphate transfer within the molecule of phosphatidylinositol from glycerol OH to 2-OH of myo-inositol, resulting in diacylglycerol and myo-inositol 1,2-cyclic phosphate. Next myo-inositol 1,2-cyclic phosphate is hydrolyzed by the enzyme to inositol 1-phosphate. Since the reaction rate of the first step (phosphotransferase) is 1000 times as much as that of the second step (cyclic phosphodiesterase) myo-inositol 1,2-cyclic phosphate accumulates as one of the major products during enzyme action | Listeria monocytogenes | diacylglycerol + myo-inositol 1,2-cyclic phosphate | - |
? | |
4.6.1.13 | phosphatidylinositol + H2O | degrades synthetic phosphatidylinositols in the following order dilauroyl > dimyristoly > dioleoyl > dipalmitoyl. At first the enzyme catalyzes phosphate transfer within the molecule of phosphatidylinositol from glycerol OH to 2-OH of myo-inositol, resulting in diacylglycerol and myo-inositol 1,2-cyclic phosphate. Next myo-inositol 1,2-cyclic phosphate is hydrolyzed by the enzyme to inositol 1-phosphate. Since the reaction rate of the first step (phosphotransferase) is 1000 times as much as that of the second step (cyclic phosphodiesterase) myo-inositol 1,2-cyclic phosphate accumulates as one of the major products during enzyme action | Bacillus thuringiensis | diacylglycerol + myo-inositol 1,2-cyclic phosphate | - |
? | |
4.6.1.13 | phosphatidylinositol + H2O | at first the enzyme catalyzes phosphate transfer within the molecule of phosphatidylinositol from glycerol OH to 2-OH of myo-inositol, resulting in diacylglycerol and myo-inositol 1,2-cyclic phosphate. Next myo-inositol 1,2-cyclic phosphate is hydrolyzed by the enzyme to inositol 1-phosphate. Since the reaction rate of the first step (phosphotransferase) is 1000 times as much as that of the second step (cyclic phosphodiesterase) myo-inositol 1,2-cyclic phosphate accumulates as one of the major products during enzyme action | Bacillus cereus | diacylglycerol + myo-inositol 1,2-cyclic phosphate + D-myo-inositol 1-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.13 | phosphatidylinositol-specific phospholipase C | - |
Staphylococcus aureus |
4.6.1.13 | phosphatidylinositol-specific phospholipase C | - |
Bacillus cereus |
4.6.1.13 | phosphatidylinositol-specific phospholipase C | - |
Listeria monocytogenes |
4.6.1.13 | phosphatidylinositol-specific phospholipase C | - |
Bacillus thuringiensis |